NFL picks 12/4: Dallas Cowboys @ Detroit Lions

Dallas Cowboys
@

Detroit Lions
Thursday, December 4, 2025 at 8:15 PM ET

by Jack Chambers for Wannamakeabet..com

Detroit and Dallas meet Thursday night in a matchup that could decide seeding and momentum heading into the final month of the season. This is a high-stakes NFC tilt at Ford Field with the Lions installed as a short favorite and both offenses capable of putting up points.

Team Analysis

Dallas

  • Season overview: Dallas (6-5-1) sits one game back of Detroit and still relies on a pass-heavy attack led by Dak Prescott, who ranks among the team leaders in passing yards and touchdowns this season.
  • Recent form: Cowboys have been up-and-down but come in with momentum after a three-game stretch that included key offensive outputs; their passing attack is among the NFL’s most prolific this year.
  • Injuries/availability: Dallas has multiple names on the week’s report — Trevon Diggs was limited in practice while other defensive pieces (Jadeveon Clowney, Dante Fowler) have been listed with various ailments; monitor late-game status reports. CeeDee Lamb’s earlier season ankle issues were notable and depth usage has shifted as a result.

Detroit

  • Season overview: Detroit (7-5) has been one of the league’s highest-scoring teams (team totals and touchdown production rank near the top), mixing a dynamic passing game from Jared Goff with a balanced rushing attack.
  • Recent form: The Lions are playing with playoff urgency after a narrow stretch of games; they’ve alternated results but remain comfortably competitive at home.
  • Injuries/availability: Amon‑Ra St. Brown missed multiple practices with an ankle issue and is uncertain for Thursday; tackle Penei Sewell and CB Terrion Arnold face significant concerns (Arnold now slated for season-ending surgery). Detroit’s injury list complicates matchups vs. Dallas.

Key Matchup Factors

  • Head-to-head history

– Recent meetings have favored Detroit in notable blowouts but the series sees swings; the Lions thumped Dallas 47-9 in October 2024 but other matchups have been tighter. Expect variability.

  • Important player matchups

Dak Prescott vs. Detroit front seven — Detroit’s pass rush (led by edge play) must generate consistent pressure to disrupt Dallas’ timing and limit chunk plays. Jared Goff vs. Dallas secondary — with Detroit’s top receiver status muddy due to St. Brown’s ankle, complementary weapons and running game efficiency will be critical.

  • Key injuries and news

Terrion Arnold – season-ending shoulder surgery removes a young corner from Detroit’s rotation and impacts depth. – Amon‑Ra St. Brown – missed multiple practices; his game-day availability is a swing factor for Detroit’s game plan. – Dallas practice notes show several limited participants but Dak has continued to play through minor bumps; monitor Friday game-day reports for final statuses.

  • Home/away performance

– Detroit has proven tough at Ford Field this year and is slotted as the home favorite; Dallas has been strong offensively on the road in past stretches but Ford Field’s crowd and conditions favor the Lions.

Betting Analysis

  • Spread analysis

– Current market: Detroit -3.0 (DraftKings primary) and multiple books show the Lions hovering around the field-goal chalk with early market movement both ways depending on injury news. Public books and sharps are split; line opened larger at times and has been bet down to this mid-single-digit number. Shop margins — you can find a half-point of variance across shops.

  • Total (over/under) analysis

– The posted total is 54.5 (DraftKings). Both offenses rank among the NFL’s top units in yardage and scoring, but defensive injuries (Arnold) and receiver availability (St. Brown) can suppress Detroit’s ceiling. Historical splits and recent games suggest this game leans toward the over given Dallas’ passing explosiveness and Detroit’s scoring rhythm when healthy. That said, if St. Brown is out, the tempo could tilt lower.

  • Best value opportunities

– If Amon‑Ra St. Brown is confirmed out or limited, line value leans to taking Dallas +3 (or better) — Cowboys’ passing attack can exploit Detroit’s secondary injuries. Conversely, if St. Brown plays and is near full strength, Detroit -3 is fair value given home-field and recent offensive efficiency. Monitor game-day practice reports; the betting edge is timing your wager after official inactives are announced.

  • Prediction

– My projection: with Detroit slightly banged up but still at home, this becomes a tight, fast-paced affair that likely reaches the 50s in total points. I lean to Detroit -3 as the closing number — take the Lions and the Over 54.5 in a correlated play if St. Brown is active; if he’s inactive, pivot to Dallas +3 cash or a +moneyline hedge depending on juice. Market prices suggest the smart move is to wait for Friday’s official reports for maximum edge.

Final pick: Detroit -3 and Over 54.5 (conditional — if Amon‑Ra St. Brown is ruled out, move to Dallas +3). Play size: moderate — this is a tight divisional affair with late news risk.

Wannamakeabet’s points-based system favors correlated bets here: home favorite + offensive health = edge on the Lions; but injury volatility pushes us to stagger tickets (main ticket on Detroit -3, small hedge on Cowboys +3 if St. Brown is questionable). Shop lines, watch the Friday injury report, and get better pricing before committing.

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