November 1, 2026 | Wannamakeabet.com
Sunday’s injury picture features depleted receiving groups, offensive-line concerns and several defensive absences that could change how these games play out. Here are the five biggest headlines, followed by the matchup-by-matchup breakdown.
Sunday morning update: Questionable players remain pending final inactive announcements, released approximately 90 minutes before kickoff. All times Eastern.
Top Five Injury Headlines
- Philadelphia’s offense takes multiple hits. DeVonta Smith (WR, hamstring), Dontayvion Wicks (WR, ankle) and Lane Johnson (OT, personal) are out against Washington. Losing receiving options and protection together puts added pressure on the Eagles’ remaining offensive pieces.
- New England loses A.J. Brown and TreVeyon Henderson. Brown (WR, ankle) and Henderson (RB, illness) are out at Miami, removing two important weapons and reducing the Patriots’ flexibility.
- Denver has concerns across the lineup against Kansas City. Talanoa Hufanga (S, ankle) is out, while Jaylen Waddle (WR, chest), Garett Bolles (OT, hip), Zach Allen (DT, hamstring) and Brandon Jones (S, hamstring) are questionable.
- Buffalo is watching two targets and a starting tackle. DJ Moore (WR, shoulder), Dalton Kincaid (TE, chest) and Spencer Brown (OT, back) are questionable against Baltimore. Their availability matters to both the passing game and its protection.
- Breece Hall’s status looms over Raiders–Jets. Hall (RB, quadriceps) is questionable, while New York also faces offensive-line uncertainty and confirmed losses along its defensive front.
Baltimore Ravens at Buffalo Bills — 1 p.m.
Ravens: Vega Ioane (OG, MCL) and Jaylinn Hawkins (S, knee) are out. T.J. Tampa (CB, knee) is questionable. Baltimore loses an interior blocking option and a safety, with another defensive back awaiting clearance.
Bills: DJ Moore (WR, shoulder), Dalton Kincaid (TE, chest) and Spencer Brown (OT, back) are questionable. Greg Gaines (DT, calf), Dee Alford (CB, ankle) and TJ Parker (LB, knee) are also questionable. C.J. Gardner-Johnson (S) is suspended.
WANNA takeaway: Buffalo’s offensive availability is the first checkpoint. Missing targets and a starting tackle together would be more consequential than any one absence, while both teams have defensive-backfield concerns.
Tennessee Titans at Cincinnati Bengals — 1 p.m.
Titans: Tyjae Spears (RB, knee) and Carnell Tate (WR, shoulder) are out. Calvin Ridley (WR, hip) is questionable, leaving Tennessee at risk of losing another receiving option. John Franklin-Myers (DE, groin) and Jaylon Jones (CB, knee) are also questionable. Tommy Townsend (P, knee) is out.
Bengals: Kyle Dugger (S, quadriceps) is out. Joe Giles-Harris (LB, calf) is questionable.
WANNA takeaway: Cincinnati’s missing safety presents an opening, but Tennessee’s ability to exploit it depends partly on Ridley. His absence would further narrow an offense already missing Spears and Tate.
Arizona Cardinals at Dallas Cowboys — 1 p.m.
Cardinals: Walter Nolen (DT, ankle) and Jon Gaines (C, ankle) are out. Hjalte Froholdt (C, knee), Max Melton (CB, knee) and Andrew Wingard (S, knee) are questionable. Froholdt’s status is especially relevant with another center unavailable.
Cowboys: KaVontae Turpin (WR, ribs) and Dee Winters (LB, calf) are out. George Pickens (WR, shoulder), Luke Schoonmaker (TE, groin), Kenny Clark (DT, back) and P.J. Locke (S, foot) are questionable.
WANNA takeaway: Pickens is the biggest offensive decision for Dallas. Arizona’s interior-line and secondary questions could both become matchup problems, but the Cowboys need their receiving personnel available to maximize the opportunity.
Minnesota Vikings at Detroit Lions — 1 p.m.
Vikings: Jay Ward (S, knee) is questionable.
Lions: Roger McCreary (CB, foot) is questionable.
WANNA takeaway: This matchup carries fewer fresh injury decisions than most of Sunday’s slate. The remaining questions concern secondary depth, without a new skill-position absence driving the handicap.
Indianapolis Colts at Jacksonville Jaguars — 1 p.m.
Colts: Justin Walley (CB, knee) and Anthony Gould (WR, concussion) are out. Drew Ogletree (TE, knee) and Bryce Boettcher (LB, groin) are questionable.
Jaguars: Antonio Johnson (S, ankle) is out. Jakobi Meyers (WR, hamstring) is questionable.
WANNA takeaway: Meyers is the key offensive name to check. Jacksonville has an opportunity against a secondary missing Walley, but losing Meyers would reduce its options; Johnson’s absence also creates a coverage concern on the other side.
Las Vegas Raiders at New York Jets — 1 p.m.
Raiders: Jackson Powers-Johnson (OG, back) is questionable, creating an interior protection and run-blocking concern.
Jets: Breece Hall (RB, quadriceps) and Dylan Parham (OG, knee) are questionable. Max Mitchell (OT, concussion) and Joseph Ossai (DE, ankle) are out, while David Bailey (DE, groin) is doubtful.
WANNA takeaway: Hall’s availability matters, but the blocking situation belongs in the same conversation. New York’s defensive-edge losses could also ease the matchup for Las Vegas, particularly if Bailey cannot go.
Cleveland Browns at Pittsburgh Steelers — 1 p.m.
Browns: Myles Harden (CB, hamstring) and Daniel Thomas (S, ankle) are questionable.
Steelers: Brandin Echols (CB, hamstring) and Doneiko Slaughter (CB, hamstring) are out. Ben Skowronek (WR, calf) is questionable.
WANNA takeaway: Pittsburgh’s confirmed cornerback absences are the clearest injury concern. Cleveland could find favorable coverage matchups, although that alone is not enough to turn a divisional game into an automatic over.
Atlanta Falcons at Tampa Bay Buccaneers — 1 p.m.
Falcons: Brian Robinson (RB, hamstring), Divine Deablo (LB, forearm) and Billy Bowman (S, hamstring) are out. James Pearce (LB) is suspended. Olamide Zaccheaus (WR, shoulder), Samson Ebukam (LB, hamstring), Charles Snowden (LB, back) and Avieon Terrell (CB, illness) are questionable.
Buccaneers: Emeka Egbuka (WR, foot) is out. Kenny Gainwell (RB, hip) and Luke Goedeke (OT, calf) are questionable.
WANNA takeaway: Atlanta’s defensive absences create opportunities for Tampa Bay, but Egbuka’s absence and Goedeke’s uncertain availability complicate the response. The Buccaneers’ protection deserves as much attention as their receiving depth.
Los Angeles Chargers at Los Angeles Rams — 4:05 p.m.
Chargers: Kayode Awosika (OG, lower leg), Deane Leonard (CB, concussion) and Brenen Thompson (WR, quadriceps) are out. Donte Jackson (CB, hamstring) and Rodney Shelley (CB, hamstring) are questionable, putting additional pressure on cornerback depth.
Rams: Trent McDuffie (CB, groin), Coleman Shelton (C, hip), Colby Parkinson (TE, ribs) and Jordan Whittington (WR, back) are questionable. Joe Cardona (LS, ankle) is doubtful, adding a potential special-teams concern.
WANNA takeaway: The Chargers’ cornerback situation could be the most exploitable weakness, especially if Jackson cannot play. For the Rams, Shelton’s availability affects protection, while McDuffie’s status matters to their own coverage.
Kansas City Chiefs at Denver Broncos — 4:25 p.m.
Chiefs: Mansoor Delane (CB, shoulder) is out.
Broncos: Talanoa Hufanga (S, ankle) is out. Jaylen Waddle (WR, chest), Garett Bolles (OT, hip), Zach Allen (DT, hamstring) and Brandon Jones (S, hamstring) are questionable.
WANNA takeaway: Denver has the more consequential collection of decisions. Waddle and Bolles affect offensive execution, Allen affects pressure up front, and Jones’s absence alongside Hufanga would further weaken the safety group.
New England Patriots at Miami Dolphins — 4:25 p.m.
Patriots: A.J. Brown (WR, ankle) and TreVeyon Henderson (RB, illness) are out. Carlton Davis (CB, neck) and Christian Elliss (LB, chest) are questionable.
Dolphins: Kadyn Proctor (OG, concussion) is out. JuJu Brents (CB, neck) and Reese Taylor (CB, quadriceps) are questionable.
WANNA takeaway: New England loses both a major receiving threat and a backfield weapon. Miami’s cornerback concerns could soften that blow, but the Patriots’ reduced offensive flexibility remains the central injury angle.
Philadelphia Eagles at Washington Commanders — 8:20 p.m.
Eagles: DeVonta Smith (WR, hamstring), Dontayvion Wicks (WR, ankle), Britain Covey (WR, knee), Lane Johnson (OT, personal), Jihaad Campbell (LB, hamstring) and Jonathan Jones (CB, hamstring) are out.
Commanders: Javon Kinlaw (DT, knee) and Daron Payne (DT, foot) are out. Treylon Burks (WR, foot), John Bates (TE, shoulder) and Charles Omenihu (DE, groin) are questionable.
WANNA takeaway: Philadelphia’s depleted receiving group and missing right tackle are major obstacles, but Washington’s losses at defensive tackle offer a potential route through the running game. The key is whether the Eagles can sustain drives without relying heavily on their shorthanded passing attack.
Before locking in your WANNA picks: Prioritize the final decisions on Breece Hall (RB), George Pickens (WR), Buffalo’s offensive trio and Denver’s four questionable starters. Those announcements could materially change the matchups described above.