College Football Picks 11/15: Michigan @ Northwestern

Game Time: Saturday, November 15, 2025 at 12:00 PM ET

The Michigan Wolverines (7-2, 5-1 Big Ten) are set to face the Northwestern Wildcats (5-4, 3-3 Big Ten) on November 15, 2025, at Wrigley Field in Chicago. This matchup marks the 78th meeting between these two conference rivals, with Michigan leading the series.

Team Analysis

Michigan Wolverines

Michigan enters this game with a strong 7-2 record, including a 5-1 mark in Big Ten play. The Wolverines have demonstrated a balanced offensive attack, averaging 409.4 yards per game, with 223.8 yards on the ground (12th in FBS) and 185.7 yards through the air. Their scoring offense averages 28.1 points per game. Defensively, Michigan has been impressive, allowing just 304 yards per game (19th in FBS) and 17.2 points per game (13th in FBS). The Wolverines’ rushing defense is particularly stout, surrendering only 100.2 yards per game (12th in FBS).

Northwestern Wildcats

Northwestern comes into this matchup with a 5-4 record and a 3-3 conference standing. The Wildcats’ offense has struggled, ranking 97th in the nation with 351.3 yards per game. Their passing attack averages 169.9 yards per game (119th in FBS), while the rushing offense contributes 181.4 yards per game (42nd in FBS). Northwestern scores an average of 21.9 points per game (108th in FBS). On defense, the Wildcats allow 324.0 yards per game (32nd in FBS) and 19.1 points per game (21st in FBS). Their passing defense is particularly strong, ranking 21st in the nation with 181.1 yards allowed per game.

Key Matchup Factors

Head-to-Head History

In their last two meetings, Michigan has dominated Northwestern, winning both matchups by significant margins. The most recent encounter was a 50-6 victory for the Wolverines on November 23, 2024.

Important Player Matchups

For Michigan, running back Justice Haynes has been a standout, rushing for 857 yards and 10 touchdowns this season. Quarterback Bryce Underwood has also been effective, throwing for 1,671 yards with seven touchdowns and three interceptions. Defensively, linebacker Derrick Moore leads the team with 8.5 sacks, ranking eighth nationally.

Northwestern’s offense revolves around quarterback Preston Stone, who has passed for 1,522 yards with 11 touchdowns and nine interceptions. Running back Caleb Komolafe has been productive, accumulating 726 rushing yards and eight touchdowns. Defensively, linebacker Robert Fitzgerald leads the team with 69 tackles.

Injuries and News

As of the latest reports, there are no significant injury updates for either team. Both squads are expected to be at full strength for this matchup.

Home/Away Performance Trends

Michigan has been strong on the road, holding a 2-2 record away from home this season. Northwestern has struggled at home, with a 1-3 record in home games.

Betting Analysis

Point Spread Analysis

Michigan enters this game as a 10.5-point favorite. Given their superior overall performance, especially on defense, the Wolverines are well-positioned to cover the spread. Their ability to control the line of scrimmage and limit Northwestern’s offensive opportunities should lead to a comfortable victory.

Moneyline Analysis

The moneyline odds favor Michigan heavily, reflecting their strong season and recent dominance over Northwestern. While Northwestern has the potential for an upset, the likelihood of Michigan securing a win is high.

Total (Over/Under) Analysis

The over/under for this game is set at 41.5 points. Considering Michigan’s potent offense and Northwestern’s struggles to score, it’s reasonable to expect a total score that leans toward the under. Michigan’s defense is likely to stifle Northwestern’s offense, keeping the scoring low.

Value Betting Opportunities

Betting on Michigan to cover the 10.5-point spread appears to be a solid value bet. Additionally, wagering on the under for the total points scored aligns with the expected low-scoring nature of the game.

Prediction

Michigan is poised to continue its dominance over Northwestern, leveraging a strong defensive performance and an efficient offense to secure a decisive victory. The Wolverines’ ability to control the game tempo and limit Northwestern’s scoring opportunities will be key to their success.

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